產品櫥窗
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Tobramycin
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產品型號：101-32986-56-4 商品規格： |
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3′-Deoxykanamycin B, Nebramycin Factor 6, O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine
Formular: C18H37N5O9
MW: 467.51
Description
Tobramycin is an aminoglycoside compound derived from kanamycin B and displays antibiotic and bacteriostatic activity against gram-negative bacteria
After entering the cells, it binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and interferes with the initiation complex between messenger RNA and the 30S subunit, consequently inhibiting the protein synthesis process leading to bacterial cell death
Tobramycin also can interfere with protein elongation since it can induce misreading of the mRNA template, and cause incorrect amino acids to be incorporated into the growing polypeptide chain
Applications
to study the effect of tobramycin on bacteriophage infected biofilms
to study the effects of antibiotics on Pseudomonas aeruginosa strain
as a comparator antibiotic
MW: 467.51
Description
Tobramycin is an aminoglycoside compound derived from kanamycin B and displays antibiotic and bacteriostatic activity against gram-negative bacteria
After entering the cells, it binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and interferes with the initiation complex between messenger RNA and the 30S subunit, consequently inhibiting the protein synthesis process leading to bacterial cell death
Tobramycin also can interfere with protein elongation since it can induce misreading of the mRNA template, and cause incorrect amino acids to be incorporated into the growing polypeptide chain
Applications
to study the effect of tobramycin on bacteriophage infected biofilms
to study the effects of antibiotics on Pseudomonas aeruginosa strain
as a comparator antibiotic
Store at 4°C.