產品櫥窗
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Corticosterone >98%
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產品型號：101-50-22-6 商品規格： |
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17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B
Formular: C21H30O4
MW: 346.46
Corticosterone is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect.
Applications
Corticosterone applications include its use in treating inflammatory conditions like arthritis and skin diseases by reducing inflammation and suppressing the immune system. In psychiatry, it's explored for managing immune dysregulation in disorders like major depression, autism, and PTSD, although it can also worsen psychiatric symptoms. Additionally, it is used in scientific research, particularly in animal models, to study stress, memory, and immune function, for instance, by supplementing drinking water in chickens.
MW: 346.46
Corticosterone is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect.
Applications
Corticosterone applications include its use in treating inflammatory conditions like arthritis and skin diseases by reducing inflammation and suppressing the immune system. In psychiatry, it's explored for managing immune dysregulation in disorders like major depression, autism, and PTSD, although it can also worsen psychiatric symptoms. Additionally, it is used in scientific research, particularly in animal models, to study stress, memory, and immune function, for instance, by supplementing drinking water in chickens.