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  • trans-Ferulic acid
  • 產品型號:101-537-98-4

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trans-4-Hydroxy-3-methoxycinnamic acid, Ferulic acid; (E)-Ferulic acid; (E)-Coniferic acid)

Formular: HOC6H3(OCH3)CH=CHCO2H
MW: 194.18

trans-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. trans-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. trans-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. trans-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

Application

 trans-Ferulic acid was used for esterification of methacrylated dextran. It was also used to study the effect of oral administration of trans-ferulic acid to c57BL mice on ethanol-induced liver injury. Furthermore, it has been used in the synthesis of new biocompatible antioxidant polymers linking trans-ferulic acid.