產品櫥窗
-
Sodium Orthovanadate, Na3VO4, >90%
|
產品型號：101-13721-39-6 商品規格： |
 |
Sodium Orthovanadate is a general competitive inhibitor for protein phosphotyrosyl phosphatases. The inhibition by Sodium Orthovanadate is reversible upon the addition of EDTA or by dilution.
Na3VO4
Sodium orthovanadate is a commonly used general inhibitor for protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. Sodium orthovanadate acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium orthovanadate is also an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK).
Gordon, J.A., 1991. Meth. Enzymol. 201: 477-482. PMID: 1943774
Huyer, G., et al. 1997. J. Biol. Chem. 272: 843-851. PMID: 8995372
M.W.: 183.91
Sodium orthovanadate is a commonly used general inhibitor for protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. Sodium orthovanadate acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium orthovanadate is also an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK).
Gordon, J.A., 1991. Meth. Enzymol. 201: 477-482. PMID: 1943774
Huyer, G., et al. 1997. J. Biol. Chem. 272: 843-851. PMID: 8995372
Store at 4°C, protect from light
Store solutions at -20℃，protect from light
Shipping at Room Temp within Taiwan; may vary elsewhere
Shipping at Room Temp within Taiwan; may vary elsewhere