塞魯士有限公司

免付費服務專線:080-007-2222

產品櫥窗

  • Erythromycin
  • 產品型號:101-114-07-8

    商品規格:

    商品售價

Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex.

C37H67NO13
M.W.: 733.93

Erythromycin, is used as a macrolide antibiotic protein synthesis inhibitor. It is widely used in cell culture applications. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria.

MF Paine.; DA Wagner.; KA Hoffmaster. Cytochrome P450 3A4 and P-glycoprotein mediate the interaction between an oralerythromycin breath test and rifampin. Clinical Pharmacology & Therapeutic. 2002, 72(5), 524-535 .
DB Clewell.; Y Yagi.; GM Dunny. Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance. Journal of Bacteriology. 1974, 117(1), 283-289.
store at 4℃