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  • Cycloheximide
  • 產品型號:101-66-81-9

    商品規格:

    商品售價

an antibiotic produced by S. griseus. Synonym: 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A

C15H23NO4
M.W.: 281.35
Assay: >97.1%
Potency: 955 units/mg
Cycloheximide is soluble in Chloroform, Ethanol and Methanol.

Cycloheximide is an antibiotic which acts as an inhibitor of protein synthesis in eukaryotes but not prokaryotes. Cycloheximide is used primarily in the selection wild type CAN1, CYH2 and LYS2 genes.

Cycloheximide's(CHX) main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.

Lin W, Hsu, Y., Cycloheximide-induced cPLA(2) activation is via the MKP-1 down-regulation and ERK activation., 2000., 12(7):, 457-461..

Stock Conc.: 10 mg/mL in water or ethanol, Store at -20°C
Working Conc.: 10 ug/mL
Handling: Warning! Toxic. Wear gloves/mask when handling this product. Avoid contact by all modes of exposure. Store in Tightly Sealed Vial.

Store at -20℃

Very toxic!