產品櫥窗
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AEBSF
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產品型號：101-30827-99-7 商品規格： |
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Serine Protease Inhibitor. Synonym: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
C8H10FNO2S · HCl
M.W.: 239.69
Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM.
Less toxic alternative to PMSF, pH stable.
AEBSF irreversibly inactivates thrombin and other serine proteases (e. g. chymotrypsin, kallikrein, plasmin, proteinase K, trypsin) by sulfonylation of a functional group in the active center of the enzyme. AEBSF (LD50 oral, mouse 2.8g/kg) is a substantially less toxic substitute for PMSF and DFP.
Stock Conc.: 20-100mM in water or buffer, -20℃, stable for 2 months
Working Conc.: 0.1-2mM
Walsmann, P. et al. (1972) Acta biol. med. germ. 28, 577-85.
M.W.: 239.69
Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM.
Less toxic alternative to PMSF, pH stable.
AEBSF irreversibly inactivates thrombin and other serine proteases (e. g. chymotrypsin, kallikrein, plasmin, proteinase K, trypsin) by sulfonylation of a functional group in the active center of the enzyme. AEBSF (LD50 oral, mouse 2.8g/kg) is a substantially less toxic substitute for PMSF and DFP.
Stock Conc.: 20-100mM in water or buffer, -20℃, stable for 2 months
Working Conc.: 0.1-2mM
Walsmann, P. et al. (1972) Acta biol. med. germ. 28, 577-85.
Store at 4℃