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  • Arginine monohydrochloride (L-Arginine)
  • 產品型號:101-1119-34-2

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Synonym: (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride

C6H14N4O2 · HCl
M.W. = 210.66

Physical State : Solid
Appearance :  Colorless crystalline powder
Color : White
Purity : >98.5%
Solubility :  1 M in H2O at 20 °C, clear, colorless

L-Arginine is one of the three amino acids with basic side chains, and is very hydrophilic in character. It contains a guanidino group in the side chain, and this moiety is protonated at physiological pH. Arginine is biosynthesized in the kidneys from citrulline, whose precursor is glutamate via the formation of ornithine.
In amino acid degradation in vivo, arginine is hydrolyzed to urea and ornithine by arginase. Arginine can be metabolized to glutamate, which in turn is converted to alpha-ketoglutarate for entry into the citric acid cycle.

L-Arginine is used in cell culture as a component of MEM amino acids solution
Cells utilize L-arginine as a precursor for the production of nitric oxide (NO), which is an activator of guanylyl cyclase and leads to the production of the second messenger cGMP. 

Virulence gene expression in a tRNA modificationdeficient mutant of Shigella flexneri has been modulated by the addition of L-arginine.

This product is soluble in water (50 mg/ml), yielding a clear, colorless solution.
Store at Room Temperature.